
LIST OF PRIMARY CAUSES OF RENAL DISEASE
Item 17. Primary cause of renal failure should be completed by the attending physician from the list below. Enter the
ICD-10-CM code to indicate the primary cause of end stage renal disease. If there are several probable causes of renal failure,
choose one as primary. An ICD-10-CM code is effective as of February 1, 2022.
Diabetes
E10.22 Type 1 diabetes mellitus with diabetic chronic
kidney disease
E10.29 Type 1 diabetes mellitus with other diabetic
kidney complication
E11.21 Type 2 diabetes mellitus with diabetic
nephropathy
E11.22 Type 2 diabetes mellitus with diabetic chronic
kidney disease
E11.29 Type 2 diabetes mellitus with other diabetic
kidney complication
Glomerulonephritis
N00.8 Acute nephritic syndrome with other
morphologic changes
N01.9 Rapidly progressive nephritic syndrome with
unspecified morphologic changes
N02.8 Recurrent and persistent hematuria with other
morphologic changes
N03.0 Chronic nephritic syndrome with minor
glomerular abnormality
N03.1 Chronic nephritic syndrome with focal and
segmental glomerular lesions
N03.2 Chronic nephritic syndrome with diffuse
membranous glomerulonephritis
N03.3 Chronic nephritic syndrome with diffuse
mesangial proliferative glomerulonephritis
N03.4 Chronic nephritic syndrome with diffuse
endocapillary proliferative glomerulonephritis
N03.5 Chronic nephritic syndrome with diffuse
mesangiocapillary glomerulonephritis
N03.6 Chronic nephritic syndrome with dense deposit
disease
N03.7 Chronic nephritic syndrome with diffuse
crescentic glomerulonephritis
N03.8 Chronic nephritic syndrome with other
morphologic changes
N03.9 Chronic nephritic syndrome with unspecified
morphologic changes
N04.0 Nephrotic syndrome with minor glomerular
abnormality
N04.1 Nephrotic syndrome with focal and segmental
glomerular lesions
N04.2 Nephrotic syndrome with diffuse membranous
glomerulonephritis
N04.3 Nephrotic syndrome with diffuse mesangial
proliferative glomerulonephritis
N04.4 Nephrotic syndrome with diffuse endocapillary
proliferative glomerulonephritis
N04.5 Nephrotic syndrome with diffuse
mesangiocapillary glomerulonephritis
N04.6 Nephrotic syndrome with dense deposit disease
N04.7 Nephrotic syndrome with diffuse crescentic
glomerulonephritis
N04.8 Nephrotic syndrome with other morphologic
changes
N04.9 Nephrotic syndrome with unspecified
morphologic changes
N05.9 Unspecified nephritic syndrome with unspecified
morphologic changes
N07.0 Hereditary nephropathy, not elsewhere classified
with minor glomerular abnormality
Interstitial nephritis/pyelonephritis
N10 Acute tubulo-interstitial nephritis
N11.9 Chronic tubulo-interstitial nephritis, unspecified
N13.70 Vesicoureteral-reflux, unspecified
N13.8 Other obstructive and reflux uropathy 2
Transplant complications
T86.00 Unspecified complication of bone marrow
transplant
T86.10 Unspecified complication of kidney transplant
T86.20 Unspecified complication of heart transplant
T86.40 Unspecified complication of liver transplant
T86.819 Unspecified complication of lung transplant
T86.859 Unspecified complication of intestine transplant
T86.899 Unspecified complication of other transplanted
tissue
Hypertension/large vessel disease
I12.0 Hypertensive chronic kidney disease with stage 5
chronic kidney disease or end stage renal disease
I12.9 Hypertensive chronic kidney disease with stage
1through stage 4 chronic kidney disease, or
unspecified chronic kidney disease
I15.0 Renovascular hypertension
I15.8 Other secondary hypertension
I75.81 Atheroembolism of kidney
Cystic/hereditary/congenital/other diseases
E72.04 Cystinosis
E72.53 Hyperoxaluria
E75.21 Fabry (Anderson) disease
N07.8 Hereditary nephropathy, not elsewhere classified
with other morphologic lesions
N31.9 Neuromuscular dysfunction of bladder,
unspecified
Q56.0 Hermaphroditism, not elsewhere classified
Q60.2 Renal agenesis, unspecified
Q61.19 Other polycystic kidney, infantile type
Q61.2 Polycystic kidney, adult type
Q61.4 Renal dysplasia
Q61.5 Medullary cystic kidney
Form CMS-2728-U3 (06/2025) 6